Mysterious Unfruitfulness: Here we go again...IVF#3

About Me

2 years to conceive a baby is the last thing I thought could happen to us...

Let me tell you a bit about myself. I'm 25 and my husband is 27. We have been together since Oct 13, 2000 - I was 16 & he was 18. We've got married Dec 24, 2006. We started trying to conceive in February 2007 with no success.

In September 2007 we were referred to our current doctor (RE) and she specializes in Gynecologic Reproductive Endocrinology & Infertility MSc, MD, FRCSC at fertility clinic in Toronto. Me and my husband did many test which all came back with great results. We were tested through Sonohysterogram, Laporoscopy, Hysteroscopy, Hysterosalpingogram (HSG), Semen DNA Fragmentation to name a few...

We did 3 IUI's; Then we decided to start doing IVF to increase our chances. Unfortunately, we found out that I have unexplained poor response to medications. We spent over $36,000 out of the pocket just in 2007 & 2008 for all our procedures. We had 4 failed IVF attempts, some canceled after weeks of expensive injections. Every cycle was a heartbreak and the pain never goes away.

Our diagnosis is UNEXPLAINED INFERTILITY

Unexplained poor responder

Unexplained elevated prolactin

Natural - Feb.’07-Oct. ’07;
IUI#1 - Nov '07- Clomid 50mg (cd5-9); HCG; Progesterone 400g;
IUI#2 - Jan '08- Clomid 50mg (cd5-9); HCG; Progesterone 400mg;
IVF#1 - Long Agonist Protocol; Feb '08 - BCP; Mar '08 - Suprefact / Puregon 175IU; Canceled after 9 weeks of injections due to 3.2cm cyst on the right ovary
IVF#2 - Long Agonist Protocol; April '08 BCP; May '08 - Puregon 200 IU/Orgalutran 250 mg; ER May 14 - ET May 17; 5 eggs-3 mature-2 fertilized; Day 3 transfer; transferred two 8-cell & 7-cell grade 1 embies; Progesterone 600mg;
Natural - June ’08; Aspirin 81mg/Pre-Seed;
IVF#3 - Short Antagonist Protocol; July '08 - Canceled after 10 days of injections due to elevated prolactin 36.6 & poor response; only 8 follicles and not developing
IVF#4 - Short Antagonist Protocol; Aug/Sept' 08 -Gonal-f (225iu)/Menopur (150iu); Cetrotide (250mg);Ovidrel 10,000 IU; Progesterone in oil injections (50mg), Aspirin (81mg) Cancelled after 12 days of injections (less than 7 follicles); Later converted to IUI#3
IVF#5 - Estrogen Priming with MicroFlare Protocol; Oct '08 - Start Estrace Oct5 (7DPO); Stop next CD2 after AF (Oct11) start stim with Gonal-F (450iu) & microdose of Lupron/Suprefact (0.05iu); Took Aspirin 81 mg; Almost canceled due to poor response after 13 days of injections (only 6 follicles developing) + ovarian cysts; ER on cycle day 21 (!!!) after 18 days of stims; Got 10 eggs; 7 mature; 5 fertilized with ICSI; Day 5 transfer of 2 blastocysts (2AB both); one was hatching; None to freeze, all arrested; Crinone 8% & Estrace 6mg after ET

Greater than 50% of patients achieve pregnancy on their first IVF cycle.
Close to 50% of patients who had a second cycle also achieved pregnancy.
Finally, 40% of patients who did a third cycle achieved a clinical pregnancy.

Statistically, most people have become pregnant by their third cycle.

Thursday, June 12, 2008

Here we go again...IVF#3

Had my follow-up/review appointment with RE today. So once AF arrives from this "natural" cycle, which I am not hoping will work...

We are doing it again! Yep! All over again!

July 2008 - IVF#3

Hoping to get more eggs and this time, not going to be on BCP or any kind of pre-suppression because last IVF did not do any good for me and I was over suppressed. Also, if everything goes well, we're going for a 5 day transfer this time.

All of my medications were switched, which is good. So now I will be on:

Gonadotropins (Follicle Stimulation) injections of:

GnRH antagonists (Ovulation Prevention) injection of: